Agreement regarding the sales of Mirol Eye Drop 0.5% with Kyorin Pharmaceutical

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Agreement for The consignment of Mirol Eye Drop 0.5%(August 3, 2000)
Kyorin Pharmaceutical Co., Ltd. and KAKEN PHARMACEUTICAL CO., LTD. signed an agreement regarding a marketing cooperation on Mirol (L-bunolol) Eye Drop 0.5%, an agent for the treatment of glaucoma and ocular hypertension. Kyorin obtained a license of the agent from Allergan, Inc. (U.S.A.) and got a sales and manufacturing approval from Japanese Health Authority as of July 3, 2000. Under this agreement, Kyorin consigned the product for sale in Japan to KAKEN.

In the process of restructuring the operation, Kyorin has intended to put emphasis on three marketing areas of Respiratory, Otorhinology and Urology

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