December 15, 2016

Takeda Pharmaceutical Company Limited

Takeda Announces Sale of Shareholding in
Wako Pure Chemical Industries, Ltd.
to Fujifilm Corporation

Osaka, Japan, December 15, 2016 - Takeda Pharmaceutical Company Limited （TSE: 4502） today held a meeting of the Board of Directors and adopted a resolution to sign an agreement （“Tender Agreement”） with Fujifilm Corporation （Head Office: Minato-ku, Tokyo, “Fujifilm”） to transfer its shareholding in Wako Pure Chemical Industries, Ltd. （Head Office: Chuo-ku, Osaka, “Wako Pure Chemical”）, a consolidated subsidiary through the tender offer bid （“TOB”） to be launched by Fujifilm in late February. After adopting the resolution, Takeda entered into the Tender Agreement with Fujifilm.

This is a positive strategic move for Fujifilm, Wako Pure Chemical, and Takeda. The sale price is 198.5 billion yen and Takeda expects to post a one-time pre-tax gain of approximately 100 billion yen in its FY2017 consolidated income statement.

1.　Rationale to tender in the TOB
Wako Pure Chemical was established in 1922 with the spin-off of the chemical agent division of Takeda. It has been developing and producing high-grade products as a comprehensive laboratory reagent manufacturer, and addresses needs in cutting-edge research areas under its management philosophy, “We hope to serve the well-being of the public through our efforts to promote the development of scientific technologies and progress of academic research.” At present, by leveraging its core competency of proprietary technological capabilities, Wako Pure Chemical is able to serve the diverse needs of scientists, medical professionals and the industrial world in general through its three key businesses of “Laboratory Chemicals”, “Specialty Chemicals” and “Clinical Diagnostic Reagents”.

In order to achieve sustainable growth as a global pharmaceutical company, Takeda aims to discover and develop innovative drugs by focusing its R&D efforts on the areas of Oncology, Gastroenterology （GI） and Central Nervous System （CNS）, plus Vaccines. After carefully considering and examining options for Wako Pure Chemical’s business, Takeda has concluded that Wako Pure Chemical can better accelerate its development with the support of Fujifilm, which has maintained a long-term capital and business relationship with Wako Pure Chemical and has a mid- to long-term growth strategy centered on the business fields of “Healthcare” and “Highly Functional Materials”. Wako Pure Chemical, at its meeting of the Board of Directors held on December 15, 2016, adopted a resolution to express its supportive opinion for the TOB and to recommend its shareholders to tender their shares.

In the Tender Agreement, Takeda and Fujifilm agreed that, after the completion of the undermentioned Share Repurchase by Wako Pure Chemical, Takeda will tender all of its remaining shareholding in Wako Pure Chemical for the TOB and have Nihon Pharmaceutical Industry Co.,　Ltd. （“Nihon Pharmaceutical”）, one of Takeda’s subsidiaries, tender all of its remaining shareholding in Wako Pure Chemical. The Tender Agreement also sets the following conditions precedent for Takeda and Nihon Pharmaceutical （“Takeda Group”） to tender: 1） the TOB is legally and effectively commenced and not withdrawn, 2） each of the representations and warranties^*1 made by Fujifilm in the Tender Agreement is true and correct in all material respects, 3） there are no laws, regulations and judicial decisions or the like that would restrict or prohibit the consummation of the TOB, 4） Fujifilm has performed or complied with all of its obligations, covenants and conditions^*2 required to perform or comply prior to the commencement of the TOB under the Tender Agreement, 5） Fujifilm has completed necessary procedures and formalities under competition law in Japan and overseas and 6） the Share Repurchase has been completed. However, Takeda is not restrained from tendering or having Nihon Pharmaceutical tender for the TOB by waiving all or part of those conditions precedent at its own discretion. Takeda and Fujifilm also agreed that Takeda Group may not tender or may cancel the tender that has been made, in such a case that a third party commences a tender offer bid （the “Counter TOB”） for shares in Wako Pure Chemical with a considerably higher offer price than the TOB price, and that Takeda makes a reasonable decision after receiving a legal opinion letter to the effect that tendering for the TOB is reasonably considered to breach the duty of due care of a prudent manager for Takeda’s directors, and furnishes the letter to Fujifilm.

^*1 In the Tender Agreement, Fujifilm represents and warrants that （i） as of the execution date of the Tender Agreement and as of the commencement date and the settlement date of the TOB, 1） Fujifilm is lawfully established and validly existing, 2） Fujifilm has necessary authority and power to execute and perform the Tender Agreement, 3） the Tender Agreement is legally binding and enforceable against Fujifilm, 4） the execution and performance of the Tender Agreement and the execution of the TOB are not in conflict with any laws and regulations, 5） Fujifilm has obtained all permission or authorization necessary for the execution and performance of the Tender Agreement prior to the execution date of the Tender Agreement and the commencement date of the TOB and （ii） Fujifilm has financial capacity to execute the TOB as of the settlement date of the TOB

^*2 In the Tender Agreement, the obligations, covenants and conditions to be performed or complied with by Fujifilm prior to the commencement date of the TOB include 1） the obligation not to place any objection to Takeda’s tender for the Share Repurchase and Wako Pure Chemical’s completion of the procedures of the Share Repurchase, 2） the obligation to notify Takeda in case there is or may be any breach in Fujifilm’s representations and warranties, Takeda’s non-satisfaction of conditions precedent or breach of Fujifilm’s obligations set forth in the Tender Agreement, 3） the obligation to keep confidentiality, 4） the obligation to use best efforts in relation to necessary procedures and formalities under competition law in Japan and overseas, 5） the indemnification for the breach of the representations and warranties or obligations in the Tender Agreement, 6） the obligation to bear own expenses incurred in relation to the preparation, the execution and the performance of the Tender Agreement, 7） the prohibition from assignment of any of the rights or obligations in the Tender Agreement and 8） the obligation to consult in good faith.

At its Board of Directors meeting held on December 15, 2016, Wako Pure Chemical also adopted a resolution to submit an agenda for an extraordinary shareholders’ meeting to be held on February 6, 2017, prior to the TOB, concerning the repurchase of its own shares, up to approximately 97 billion yen, at the same price as the TOB price （the “Share Repurchase”, collectively, together with the TOB, the “Share Transfer”）. Wako Pure Chemical will implement the Share Repurchase subject to shareholders’ approval. If Wako Pure Chemical implements the Share Repurchase, Takeda will transfer all of Takeda's Group shareholding （“Takeda’s Shareholding”） for 198.5 billion yen in total, by tendering part of Takeda’s shareholdings for the Share Repurchase and by tendering all the remaining Takeda’s Shareholding for the TOB.

2.　Overview of Wako Pure Chemical

（1）Company name	Wako Pure Chemical Industries, Ltd.
（2）Headquarters	1-2 Doshomachi 3-Chome, Chuo-ku, Osaka
（3）Name and title of representative	Shinzo Kobatake, President
（4）Business description	Production and distribution of laboratory chemicals, specialty chemicals and diagnostic reagents
（5）Capital	2,340 million yen （as of September 30, 2016）
（6）Date of establishment	June 5, 1922
（7）Major shareholders and percentage of shares held （as of September 30, 2016）1	Takeda Pharmaceutical Company Limited		69.42%
	Fujifilm Corporation		9.50%
	Wako Pure Chemical Employee Shareholding Association		1.68%
（8）Relationships between Takeda and Wako Pure Chemical2	Capital relationship	Takeda holds 69.75% of the　outstanding shares of Wako Pure Chemical （including 0.33% indirectly held） as of September 30, 2016
	Personnel relationship	Takeda dispatches an auditor to Wako Pure Chemical
	Transactional relationship	Takeda purchases products and materials from Wako Pure Chemical. Wako Pure Chemical also loans to Takeda.
（9）Operating result and financial conditions for the last three years （consolidated）
Accounting period	Fiscal year ended March 2014	Fiscal year ended March 2015	Fiscal year ended March 2016
Consolidated net assets （million yen）	119,919	124,429	125,355
Consolidated total assets （million yen）	149,986	152,281	152,853
Consolidated net assets per share （yen）	3,598.84	3,734.16	3,837.40
Consolidated sales （million yen）	75,064	77,602	79,391
Consolidated operating income （million yen）	7,205	7,672	7,761
Consolidated ordinary income （million yen）	7,360	7,837	7,849
Net income attributable to shareholders of parent （million yen）	4,566	5,080	5,662
Consolidated earnings per share （yen）	137.05	152.50	172.15
Dividend per share （yen）	83.00	85.00	88.00

^{（Note 1）} The percentages of shares in "Major shareholders and percentage of shares held" corresponds to the numbers in the 144 ^th semiannual report of Wako Pure Chemical.

^{（Note 2）} The ratio of shareholding to the outstanding shares is rounded down to third decimal point.

3.　Overview of Fujifilm

（1）Company name	Fujifilm Corporation
（2）Headquarters	26-30, Nishiazabu 2-chome, Minato-ku, Tokyo
（3）Name and title of representative	Kenji Sukeno, President
（4）Business description	Development, production, sales, and service of 1） Imaging Solutions （color films, digital cameras, color paper・services・equipment for photography printing, instant photo systems, optical devices） and 2） Information Solutions （medical systems, life science products, pharmaceutical products, graphic systems, flat panel display materials, recording media, electronic materials）
（5）Capital	40,000 million yen （as of December 15, 2016）
（6）Date of establishment	October 2, 2006
（7）Major shareholders and percentage of shares held	Fujifilm Holdings Corporation		100.00%
（8）Relationships between Takeda and Fujifilm	Capital relationship	Not Applicable
	Personnel relationship	Not Applicable
	Transactional relationship	Not Applicable
	Whether Fujifilm constitutes a related party	Not Applicable

4.　Change in Ownership Ratio of Shares through the Share Transfer

（1）Number of shares held prior to the transfer	23,259,242 shares （Takeda: 23,148,821 shares, Nihon Pharmaceutical1: 110,421 shares） （Number of votes：23,258） （％ of total votes2：71.78％） （as of September 30, 2016）
（2）Number of shares to be transferred3	23,259,242 shares （Takeda：23,148,821 shares, Nihon Pharmaceutical1: 110,421 shares） （Number of votes：23,258） （％ of total vote2s：71.78％） （as of September 30, 2016） （Transfer price4：198,517,630,470 yen （8,535 yen per share））
（3）Number of shares held after the transfer5	0 shares （Number of votes：0） （％ of total votes：0.00％）

^{（Note 1）} Nihon Pharmaceutical is a Takeda’s consolidated subsidiary.

^{（Note 2）} The number of votes is rounded off to third decimal point.

^{（Note 3）} Takeda Group to tender part of the shareholding in Wako Pure Chemical for the Share Repurchase, in which the number of shares to be repurchased is set to be up to 11,364,967 shares.

^{（Note 4）} The transfer price above is arrived at by multiplying the number of shares to be transferred through the Share Transfer by 8,535 yen （Tender offer price of the TOB and purchase price of the Share Repurchase）.

^{（Note 5）} The number of shares held after the transfer represents the number of shares if the Share Transfer is completed and all Takeda's Shareholding is transferred.

5. Schedule of the Share Transfer

（1）Execution of the Tender Agreement	December 15, 2016
（2）Date of the extraordinary shareholder’s meeting of Wako Pure Chemical regarding the Share Repurchase	February 6, 2017 （tentative）
（3）Date of the meeting of Board of Directors and the public notice regarding the Share Repurchase	February 6, 2017 （tentative）
（4）Application deadline of the Share Repurchase	February 14, 2017 （tentative）
（5）Settlement date of the Share Repurchase	February 24, 2017 （tentative）
（6）Tender offer period of the TOB	From February 27, 2017 to April 3, 2017 （tentative）
（7）Disclosing date of result of the TOB	April 4, 2017 （tentative）
（8）Commencement date of settlement of the TOB	April 21, 2017 （tentative）

6.　Outlook
As a result of the Share Transfer, Wako Pure Chemical will be removed from Takeda's consolidated subsidiaries （FY2015 revenue: 79.4 billion yen）.
If the Share Transfer is completed, Takeda will post a one-time pre-tax gain of approximately 100 billion yen in the first quarter of FY2017. The cash impact is expected to exceed 100 billion yen. There will be no financial impact on Takeda’s FY2016 consolidated earnings forecast^*.

^*Unconsolidated financial statements
Under Japanese accounting standards, which apply to Takeda's stand-alone financial statements, the Share Repurchase and the TOB are considered to be independent transactions. Consequently, Takeda will post gains of approximately 90 billion yen concerning the Share Repurchase in the fourth quarter of FY2016 and 100 billion yen concerning the TOB in the first quarter of FY2017.

Media Contacts:
Tsuyoshi Tada
TEL:+81-33-278-2417
tsuyoshi.tada@takeda.com

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